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I really love Weight Watchers. I've been a member, going to meetings, for about a year and half, and I have lost more than 10% of my body weight! The meetings are SO great.
I agree with monkeesno1 in that you may not be a candidate for surgery (or you may not be able to afford it), so, really, the best course of action is to eat less and exercise more.
Easier said than done, I know, but there are so many inspiring stories to take comfort and strength from. The one I often reflect on is an older story ... the woman by the name of Susan Powters. You may remember her from the 1990s. She lost more than 130 pounds. I think she was close to 300 pounds when she just said "no more" or "stop the insanity" and she started by walking around the block. I remember her saying she was so heavy that her legs were banging together and she was in pain and she was embarrassed, but she knew she couldn't keep on the way she was going, so she just started moving.
Here is her web site, if you want to learn more about her.
My mother had a lap band surgery done in Novemeber of 06. She too weighed 300 pounds. She has lost a total of 90 pounds but has gained back 60. She has trouble eating and is often left unable to eat many times, and is always sick. This is a sad outcome of this surgery. While there is no quick answer the best is a natural answer. I know a women at my job who has also done the lap band, and she still eats fried chicken. Unless you change your eating habits no quick fix will ever work. I lost 90 pounds after I had my daughter. My advice is join weight watchers, its always great to chat with people in the same situation, join a gym and start off really slow. Don't be afraid. Just believe you can do it.